Androgen Deprivation Therapy and Cataract Incidence Among Elderly Prostate Cancer Patients in the United States
Jennifer Beebe-Dimmer, Hal Morgenstern, Karynsa Cetin, Cecilia Yee, Monina Bartoces, Vahakn Shahinian, Jon Fryzek, John Acquavella, Kendra L. Schwartz
20110201
2011 Mar 1
Ann Epidemiol
Androgen Deprivation Therapy and Cataract Incidence Among Elderly Prostate Cancer Patients in the United States
Ann Epidemiol. 2011 Mar;21(3):156-163, Jennifer Beebe-Dimmer, Hal Morgenstern, Karynsa Cetin, Cecilia Yee, Monina Bartoces, Vahakn Shahinian, Jon Fryzek, John Acquavella, Kendra L. Schwartz
PurposeThe side-effects associated with androgen deprivation therapy (ADT) include weight gain, dyslipidemia, and insulin resistance. As cataracts have been linked to these metabolic abnormalities, an increased risk of cataract may be another adverse consequence of ADT use.MethodsUsing data from the Surveillance, Epidemiology and End Results-Medicare database, we estimated risk of cataract associated with ADT among 65,852 prostate-cancer patients. ADT treatment was defined as at least one dose of...
