Minimally important differences were estimated for six Patient-Reported Outcomes Measurement Information System-Cancer scales in advanced-stage cancer patients

J Clin Epidemiol. 2011 May;64(5):507-516, Kathleen J. Yost, David T. Eton, Sofia F. Garcia, David Cella

Abstract

ObjectiveWe combined anchor- and distribution-based methods to establish minimally important differences (MIDs) for six Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer scales in advanced-stage cancer patients.Study Design and SettingParticipants completed 6 PROMIS-Cancer scales and 23 anchor measures at an initial (n=101) assessment and a follow-up (n=88) assessment 6–12 weeks later. Three a priori criteria were used to identify usable cross-sectional and longitudinal anchor-based...

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