Diagnostic and therapeutic management for suspected neonatal herpes simplex virus infection
S.I.M. Wolfert, E.P. de Jong, A.C.T.M. Vossen, J. Zwaveling, A.B. Te Pas, F.J. Walther, E. Lopriore
20110401
2011 May 1
J Clin Virol
Diagnostic and therapeutic management for suspected neonatal herpes simplex virus infection
J Clin Virol. 2011 May;51(1):8-11, S.I.M. Wolfert, E.P. de Jong, A.C.T.M. Vossen, J. Zwaveling, A.B. Te Pas, F.J. Walther, E. Lopriore
Abstract
BackgroundNeonatal herpes simplex virus (HSV) is a rare disease associated with high mortality and morbidity rates. HSV infection can be subdivided into 3 clinical manifestations: isolated skin, eye and mouth (SEM) disease, central nervous system (CNS) disease and disseminated disease. Consensus guidelines for diagnostic and therapeutic management are not available.ObjectivesTo evaluate the diagnostic work-up and therapeutic management in neonates with suspected or proven HSV infection.Study designRetrospective...
