Effectiveness and safety of combined antiplatelet and anticoagulant therapy: A critical review of the evidence from randomized controlled trials
Jeremy S. Paikin, Doug S. Wright, John W. Eikelboom
20110401
2011 May 1
Blood Rev
Effectiveness and safety of combined antiplatelet and anticoagulant therapy: A critical review of the evidence from randomized controlled trials
Blood Rev. 2011 May;25(3):123-129, Jeremy S. Paikin, Doug S. Wright, John W. Eikelboom
Abstract
Antiplatelet and anticoagulant drugs are effective for the prevention of arterial and venous thrombosis but patients continue to experience major cardiovascular events despite their use. Strategies to improve the effectiveness of antithrombotic therapies include selecting the optimal drug and dosing regimen, the use of combinations of antiplatelet and anticoagulant drugs and the development of new more effective drugs to replace existing therapies. Evidence from randomized controlled trials indicates...
