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A Retrospective Multicenter Analysis of Elderly Hodgkin Lymphoma: Outcomes and Prognostic Factors in the Modern Era
Outcomes and Prognostic Factors in Elderly With Hodgkin's Lymphoma
AM Evens, I Helenowski, E Ramsdale, SM Smith, et al
20111023
2011 Nov 23
Blood
A Retrospective Multicenter Analysis of Elderly Hodgkin Lymphoma: Outcomes and Prognostic Factors in the Modern Era
Blood. 2011 Nov 23;[Epub Ahead of Print], AM Evens, I Helenowski, E Ramsdale, SM Smith, et al
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Abstract
Abstract
We investigated a recent (1/99-12/09) cohort of 95 elderly Hodgkin lymphoma subjects. At diagnosis, median age was 67 years (60-89), while 61% had significant co-morbidity, 17% had a geriatric syndrome, 26% were unfit, and 13% had loss of activities of daily living (ADL). Response rate to therapy was 85%, while incidence of bleomycin lung toxicity was 32% (associated mortality rate: 25%). With 66-month median follow-up, 2-year and 5-year overall survival (OS) were 73% and 58%, respectively (advanced-stage:...