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An Analysis of Patients With Bulky Advanced Stage Ovarian, Tubal, and Peritoneal Carcinoma Treated With Primary Debulking Surgery (PDS) During an Identical Time Period as the Randomized EORTC-NCIC Trial of PDS vs Neoadjuvant Chemotherapy (NACT)
Primary Debulking Surgery Preferred Over Neoadjuvant Chemotherapy in Advanced Ovarian Cancer
DS Chi, F Musa, F Dao, RR Barakat
20120001
2012 Jan 1
Gynecol Oncol
An Analysis of Patients With Bulky Advanced Stage Ovarian, Tubal, and Peritoneal Carcinoma Treated With Primary Debulking Surgery (PDS) During an Identical Time Period as the Randomized EORTC-NCIC Trial of PDS vs Neoadjuvant Chemotherapy (NACT)
Gynecol Oncol. 2012 Jan 1;124(1):10-14, DS Chi, F Musa, F Dao, RR Barakat
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Abstract
Abstract
Objective: The recent EORTC-NCIC randomized trial comparing primary debulking surgery (PDS) to neoadjuvant chemotherapy (NACT) in advanced epithelial ovarian carcinoma (EOC) reported a median progression-free survival (PFS) of 12 months and overall survival (OS) of 30 months for both arms. Due to the equivalent survival and decreased morbidity with NACT, many now consider it the preferred approach. We analyzed the outcomes of patients treated with PDS at our institution during the same time period...
