Journal Scans
Association of Androgen Deprivation Therapy With Cardiovascular Death in Patients With Prostate Cancer
Androgen Deprivation Therapy Not Found to Increase Cardiovascular Death
PL Nguyen, Y Je, FAB Schutz, KE Hoffman, JC Hu, A Parekh, JA Beckman, TK Choueiri
20111114
2011 Dec 14
JAMA
Association of Androgen Deprivation Therapy With Cardiovascular Death in Patients With Prostate Cancer
JAMA. 2011 Dec 14;306(21):2359-2366, PL Nguyen, Y Je, FAB Schutz, KE Hoffman, JC Hu, A Parekh, JA Beckman, TK Choueiri
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Abstract
SUMMARY
OncologySTAT Editorial Team
Androgen deprivation therapy (ADT) is an often-used treatment for prostate cancer, but studies have yielded mixed results regarding the role of ADT and an increased risk of cardiovascular deaths. This highly controversial issue has been the subject of a joint statement by several medical societies and a safety warning by the US Food and Drug Administration. To address this question, this up-to-date meta-analysis from a systematic review of randomized controlled trials was performed to determine whether...
