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Chemotherapy and Human Chorionic Gonadotropin Concentrations 6 Months After Uterine Evacuation of Molar Pregnancy: A Retrospective Cohort Study
Chemotherapy and hCG Concentrations 6 Months After Molar Pregnancy
R Agarwal, S Teoh, D Short, R Harvey, PM Savage, MJ Seckl
20111029
2011 Nov 29
Lancet
Chemotherapy and Human Chorionic Gonadotropin Concentrations 6 Months After Uterine Evacuation of Molar Pregnancy: A Retrospective Cohort Study
Lancet. 2011 Nov 29;[Epub Ahead of Print], R Agarwal, S Teoh, D Short, R Harvey, PM Savage, MJ Seckl
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Abstract
Abstract
Background: Indications for chemotherapy in gestational trophoblastic disease include raised human chorionic gonadotropin (hCG) concentrations 6 months after uterine evacuation of hydatidiform mole, even when values are falling. We aimed to establish whether chemotherapy is always necessary in these patients.Methods: We retrospectively identified women registered between January, 1993, and May, 2008, at Charing Cross Hospital, London, UK, who had persistently high hCG concentrations 6 months after...