Colorectal Cancer in HIV Positive Individuals: The Immunological Effects of Treatment

Eur J Cancer. 2011 Jul 22;[Epub Ahead of Print], M Alfa-Wali, D Tait, T Allen-Mersh, P Tekkis, M Nelson, J Stebbing, A Antoniou, M Bower

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Abstract

Abstract

Background and Objectives: Since the introduction of highly active antiretroviral therapy (HAART), non-AIDS defining malignancies including colorectal cancer (CRC) have emerged as major health concerns for people living with HIV.Methods: From a prospective database of 11,112 HIV seropositive individuals, we identified 11 patients with CRC. Clinicopathological details on the presentation, treatment and outcomes were collected.Results: All were male with a median age of 50years (range 36–67) and median...

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