Comparative Outcome of Initial Therapy for Younger Patients With Mantle Cell Lymphoma: An Analysis From the NCCN NHL Database

Blood. 2012 Jan 10;[Epub Ahead of Print], AS Lacasce, JL Vandergrift, MA Rodriguez, JW Friedberg, et al

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Abstract

Abstract

New randomized trials have compared therapies in mantle cell lymphoma (MCL), and the role of aggressive induction has not been clearly defined. The NCCN Non-Hodgkin's Lymphoma Outcomes Database, a prospective cohort study collecting clinical, treatment, and outcome data at 7 NCCN centers, provides a unique opportunity to compare the effectiveness of initial therapies in MCL. Patients younger than 65 with MCL diagnosed between August 2000 and December 2008 were included if they received RHCVAD, RCHOP+HDT/ASCR,...

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