Journal Scans
Concurrent Chemoradiotherapy vs Radiotherapy Alone in Stage II Nasopharyngeal Carcinoma: Phase III Randomized Trial
Concurrent Chemoradiotherapy Improves Survival in Stage II Nasopharyngeal Cancer
QY Chen, Y-F Wen, L Guo, H-Q Mai, et al
20111004
2011 Nov 4
J Natl Cancer Inst
Concurrent Chemoradiotherapy vs Radiotherapy Alone in Stage II Nasopharyngeal Carcinoma: Phase III Randomized Trial
J Natl Cancer Inst. 2011 Nov 4;[Epub Ahead of Print], QY Chen, Y-F Wen, L Guo, H-Q Mai, et al
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Abstract
SUMMARY
OncologySTAT Editorial Team
Concurrent chemoradiotherapy (CCRT) has demonstrated benefits for the treatment of stage III/IV nasopharyngeal cancer (NPC) compared with radiotherapy (RT) alone. This study evaluated the efficacy of cisplatin-based CCRT compared with radiotherapy alone in patients with stage II NPC.Patients with stage II NPC were randomly assigned to receive RT alone or CCRT. In the CCRT arm, patients received cisplatin on a weekly basis. A total of 230 patients were enrolled, of whom 114 were randomly assigned...
