Early Outcomes for Malignant Peripheral Nerve Sheath Tumor Treated With Chemotherapy

Am J Clin Oncol. 2011 Aug 2;34(4):417-421, VM Moretti, EA Crawford, AP Staddon, RD Lackman, CM Ogilvie

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Abstract

Abstract

Objectives: Malignant peripheral nerve sheath tumors (MPNST) are rare soft-tissue sarcomas with a tendency for recurrence and metastasis. Treatment using chemotherapy is controversial, but benefit with some agents has been described. This study aimed to analyze early survival outcomes using doxorubicin and ifosfamide chemotherapy for MPNST.Methods: Pathology records at our musculoskeletal tumor center were searched for patients with a new diagnosis of MPNST between 2003 and 2008. Treatment involved...

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