Fentanyl Pectin Nasal Spray in Breakthrough Cancer Pain

J Support Oncol. 2010 Jul 1;8(4):184-190, D Taylor, V Galan, SM Weinstein, E Reyes, AR Pupo-Araya, R Rauck, for the Fentanyl Pectin Nasal Spray 043 Study Group

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Abstract

Abstract

Fentanyl pectin nasal spray (FPNS) is being developed to improve analgesic onset, treatment efficacy, and satisfaction/acceptability in treating breakthrough cancer pain (BTCP). Patients (n = 114) were entered into a randomized, placebo-controlled, double-blind, multicenter study. Patients who successfully titrated (n = 83) entered a double-blind phase; 10 episodes of BTCP were treated with the effective dose (7) or placebo (3). Pain intensity (11-point scale) and pain relief (5-point scale) were...

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