Journal Scans
Gemcitabine and Carboplatin in Carcinoma of Unknown Primary Site (CUP) in Elderly Patients: Analysis of a Phase 2 Adelaide Cancer Trials and Education Collaborative (ACTEC) Study
Gemcitabine/Carboplatin in Elderly With Carcinoma of Unknown Primary
S Bishnoi, K Pittman, S Yeend, MP Brown, B Koczwara, D Kotasek, WK Patterson, A Townsend, C Luke, TJ Price
20110905
2011 Oct 5
Journal of Geriatric Oncology
Gemcitabine and Carboplatin in Carcinoma of Unknown Primary Site (CUP) in Elderly Patients: Analysis of a Phase 2 Adelaide Cancer Trials and Education Collaborative (ACTEC) Study
Journal of Geriatric Oncology. 2011 Oct 5;[Epub Ahead of Print], S Bishnoi, K Pittman, S Yeend, MP Brown, B Koczwara, D Kotasek, WK Patterson, A Townsend, C Luke, TJ Price
TAKE-HOME MESSAGE
Abstract
Abstract
Objective: Cancer of unknown primary site (CUP) remains a significant oncological problem for the elderly. Chemotherapy is the mainstay of treatment but the ideal regimen remains uncertain. We have performed a retrospective subset analysis of a previously reported prospective phase 2 trial evaluating efficacy and toxicity of the combination of gemcitabine (G) and carboplatin (C) in elderly patients with CUP.Materials and Methods: In the original study, 51 patients with CUP, who had ECOG performance...
