Incidence of Types of Cancer Among HIV-infected Persons Compared With the General Population in the United States, 1992-2003
Ann Intern Med. 2008 May 20;148(10):728-736, P Patel, DL Hanson, PS Sullivan, RM Novak, AC Moorman, TC Tong, SD Holmberg, JT Brooks, Adult and Adolescent Spectrum of Disease Project and HIV Outpatient Study Investigators
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Abstract
Abstract
BACKGROUND: Persons who are HIV-infected may be at higher risk for certain types of cancer than the general population.OBJECTIVE: To compare cancer incidence among HIV-infected persons with incidence in the general population from 1992 to 2003. DESIGN: Prospective observational cohort studies. SETTING: United States.PATIENTS: 54,780 HIV-infected persons in the Adult and Adolescent Spectrum of HIV Disease Project (47,832 patients) and the HIV Outpatient Study (6948 patients), who contributed 157,819...
SUMMARY
OncologySTAT Editorial Team
Thanks to highly active antiretroviral therapy (HAART), the prognosis for people infected with the human immunodeficiency virus (HIV) has greatly improved and the course of acquired immune deficiency syndrome (AIDS) has been altered. One notable change has been in the types of cancers most likely to occur in HIV-infected people. Rates of HIV-related cancers have decreased, whereas rates of several non–HIV-related cancers have increased. This trend has important implications for the treatment of HIV-infected...
