Longitudinal Changes in Cardiac Function After Cisplatin-Based Chemotherapy for Testicular Cancer

Ann Oncol. 2011 Aug 29;[Epub Ahead of Print], R Altena, YM Hummel, J Nuver, AJ Smit, JD Lefrandt, RA de Boer, AA Voors, MP van den Berg, EGE de Vries, HM Boezen, JA Gietema

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Abstract

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OncologySTAT Editorial Team

Patients with testicular cancer treated with cisplatin-containing chemotherapy regimens are at increased risk over time for cardiac dysfunction. Subclinical changes in diastolic function may precede systolic failure in patients treated with anthracyclines, but it is unknown how changes in diastolic function change over time in patients treated with chemotherapy. This study investigated changes in cardiac function over time in patients with testicular cancer treated with cisplatin-based chemotherapy,...

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