Meningeal Carcinomatosis in Breast Cancer: Prognostic Factors and Outcome

J Neurooncol. 2011 Sept 1;104(2):565-572, CR de Azevedo, MR Cruz, LT Chinen, SV Peres, MA Peterlevitz, AE de Azevedo Pereira, MF Fanelli, DL Gimenes

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Abstract

Abstract

Meningeal carcinomatosis (MC) occurs in up to 5% of breast cancer patients. Few studies have evaluated prognostic markers in breast cancer patients with MC. Our aim was to describe the treatment of breast cancer patients with MC, and identify prognostic factors related to survival. Sixty breast cancer patients that had a diagnosis of MC between January 2003 and December 2009 were included. The median age was 46 years (range 27-76). Most patients had invasive ductal carcinoma (78.3%) and high histological/nuclear...

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