Journal Scans
Metastatic Angiosarcomas: Doxorubicin-Based Regimens, Weekly Paclitaxel and Metastasectomy Significantly Improve the Outcome
Prognostic Factors and Beneficial Interventions in Metastatic Angiosarcoma
N Penel, A Italiano, I Ray-Coquard, L Chaigneau, C Delcambre, YM Robin, B Bui, F Bertucci, N Isambert, D Cupissol, E Bompas, JO Bay, F Duffaud, C Guillemet, JY Blay
20110412
2011 May 12
Ann Oncol
Metastatic Angiosarcomas: Doxorubicin-Based Regimens, Weekly Paclitaxel and Metastasectomy Significantly Improve the Outcome
Ann Oncol. 2011 May 12;[Epub Ahead of Print], N Penel, A Italiano, I Ray-Coquard, L Chaigneau, C Delcambre, YM Robin, B Bui, F Bertucci, N Isambert, D Cupissol, E Bompas, JO Bay, F Duffaud, C Guillemet, JY Blay
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
Angiosarcomas are rare but aggressive soft-tissue sarcomas. Advanced stage at diagnosis, incomplete excision or inoperable primary tumor, and propensity for local and distant spread often contribute to a poor prognosis. Scant data are available to help guide treatment choices for patients with metastatic disease. Penel et al retrospectively analyzed a cohort of patients treated for metastatic angiosarcoma at 14 sarcoma centers in France between August 1996 and December 2009 to identify prognostic...