Mucinous Adenocarcinomas: Poor Prognosis in Metastatic Colorectal Cancer

Eur J Cancer. 2012 Jan 6;[Epub Ahead of Print], LJM Mekenkamp, KJ Heesterbeek, M Koopman ID Nagtegaal, et al

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Abstract

Abstract

Purpose: Mucinous histology of metastatic colorectal cancer (CRC) has been associated with poor prognosis; however this has never been assessed in large well-defined study populations treated with the current used systemic agents. We investigated the prognostic value of mucinous histology in two large phase III studies in metastatic CRC.Patients and Methods: The study population included 1010 metastatic CRC patients who were treated with chemotherapy and targeted therapies in two phase III studies....

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