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Non-Steroidal Anti-Inflammatory Drug Use Reduces Risk for Adenocarcinomas of the Esophagus and Esophagogastric Junction in a Pooled Analysis
NSAIDs Reduce Risk for Esophageal/GEJ Adenocarcinomas
LM Liao, TL Vaughan, DA Corley, AH Wu, et al
20111018
2011 Nov 18
Gastroenterology
Non-Steroidal Anti-Inflammatory Drug Use Reduces Risk for Adenocarcinomas of the Esophagus and Esophagogastric Junction in a Pooled Analysis
Gastroenterology. 2011 Nov 18;[Epub Ahead of Print], LM Liao, TL Vaughan, DA Corley, AH Wu, et al
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Abstract
Abstract
Background and Aims: Regular use of aspirin and other non-steroidal anti-inflammatory drugs (NSAID) has been reported to reduce risks for esophageal adenocarcinoma (EAC) and esophagogastric junctional adenocarcinoma (EGJA). However, individual studies have been too small to accurately assess the effects of medication type, frequency, or duration of use. We performed a pooled analysis to investigate these associations.Methods: We performed a pooled analysis of 6 population-based studies within the...