Journal Scans
Prediction of Chemotherapy Response by PET-CT in Osteosarcoma: Correlation With Histologic Necrosis
Chemotherapy Response Correlated With Histopathologic Necrosis in Osteosarcoma
J Bajpai, R Kumar, V Sreenivas, M Chand Sharma, SA Khan, S Rastogi, A Malhotra, S Gamnagatti, R Kumar, R Safaya, S Bakhshi
20110528
2011 Jun 28
Pediatr J Hematol Oncol
Prediction of Chemotherapy Response by PET-CT in Osteosarcoma: Correlation With Histologic Necrosis
Pediatr J Hematol Oncol. 2011 Jun 28;00(00):1-8, J Bajpai, R Kumar, V Sreenivas, M Chand Sharma, SA Khan, S Rastogi, A Malhotra, S Gamnagatti, R Kumar, R Safaya, S Bakhshi
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Abstract
Abstract
Background: The current standard for neoadjuvant chemotherapy (NACT) response evaluation in osteosarcoma is histopathologic necrosis (HN). However, it is accessible only after NACT completion and may get affected by confounding factors. Thus, noninvasive surrogate such as 18Fluorine-Fluorodeoxyglucose-positron emission tomography-computerized tomography (PET-CT) scan would be useful to individualize therapy.Methods: Thirty-one treatment naive osteosarcoma patients evaluated prospectively by PET-CT...
