Preoperative Versus Postoperative Radiotherapy in Soft-Tissue Sarcoma: Multi-Institutional Analysis of 821 Patients

Int J Radiat Oncol Biol Phys. 2011 Oct 1;81(2):498-505, S Sampath, TE Schultheiss, YJ Hitchcock, RL Randall, DC Shrieve, JY Wong

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Abstract

Abstract

Purpose: To assess the impact of radiotherapy (RT) sequencing with surgery on overall survival (OS), cause-specific survival (CSS), local failure, and distant failure in soft-tissue sarcoma (STS).Methods and Materials A retrospective analysis was conducted using the National Oncology Database, a proprietary database of aggregated tumor registries owned by IMPAC Medical Systems (Sunnyvale, CA). Patients with STS of all major anatomic sites who received definitive surgery and either preoperative (preop)...

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