Journal Scans
Safety of Bevacizumab in Metastatic Breast Cancer Patients Undergoing Surgery
Risk of Bevacizumab-Associated Bleeding in MBC Patients Undergoing Surgery
J Cortes, M Caralt, S Delaloge, DW Miles, et al
20111126
2011 Dec 26
Eur J Cancer
Safety of Bevacizumab in Metastatic Breast Cancer Patients Undergoing Surgery
Eur J Cancer. 2011 Dec 26;[Epub Ahead of Print], J Cortes, M Caralt, S Delaloge, DW Miles, et al
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Abstract
Abstract
Background: Evaluate the safety of surgery in relation to bevacizumab in the first-line treatment of metastatic breast cancer (mBC) in two international trials.Patients and Methods: The incidence, type and timing of post-surgical bleeding events and wound-healing complications were assessed in surgical patients in the AVastin And DOcetaxel (AVADO) (NCT00333775) and Avastin THErapy for advaNced breAst cancer (ATHENA) (NCT00448591) trials. Both study protocols followed recommendations to withhold bevacizumab...
