The Degree of Neutropenia Has a Prognostic Impact in Low Risk Myelodysplastic Syndrome

Leuk Res. 2012 Mar 1;36(3):287-292, I Cordoba, JR Gonzalez-Porras, E Such, MC Canizo, et al

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Abstract

Abstract

The severity of neutropenia in myelodysplastic syndrome (MDS) has not been completely studied. We analyzed the prognostic significance of severe neutropenia (neutrophils count <0.5×109/L) at diagnosis in 1109 patients with de novo MDS and low/intermediate-1 IPSS included in the Spanish MDS Registry. Severe neutropenia was present at diagnosis in 48 of 1109 (4%). Patients with severe neutropenia were most strongly represented within the groups of refractory cytopenia with multilineage dysplasia (40%)...

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