Journal Scans
Treatment of Colorectal Peritoneal Carcinomatosis With Systemic Chemotherapy: A Pooled Analysis of North Central Cancer Treatment Group Phase III Trials N9741 and N9841
Chemotherapy for Colorectal Peritoneal Carcinomatosis; Treatment Outcomes
J Franko, Q Shi, CD Goldman, BA Pockaj, GD Nelson, RM Goldberg, HC Pitot, A Grothey, SR Alberts, DJ Sargent
20111112
2011 Dec 12
J Clin Oncol
Treatment of Colorectal Peritoneal Carcinomatosis With Systemic Chemotherapy: A Pooled Analysis of North Central Cancer Treatment Group Phase III Trials N9741 and N9841
J Clin Oncol. 2011 Dec 12;[Epub Ahead of Print], J Franko, Q Shi, CD Goldman, BA Pockaj, GD Nelson, RM Goldberg, HC Pitot, A Grothey, SR Alberts, DJ Sargent
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
Advanced colorectal cancer (CRC)-related symptoms and complications differ by metastatic site; among the poorest prognosis is associated with peritoneal spread, especially in patients with bowel obstruction. Although in select patients with peritoneal carcinomatosis (pc), cytoreductive surgery followed by chemotherapy can result in drastically improved survival, data regarding chemotherapy-related outcomes in this setting are scarce. In this retrospective analysis, Franko et al evaluated pooled data...
