Potential implications of mesenchymal stem cells in cancer therapy
Long-Jun Dai, Mani R. Moniri, Zhi-Rong Zeng, Jeff X. Zhou, Jarrett Rayat, Garth L. Warnock
20110501
2011 Jun 1
Cancer Lett
Potential implications of mesenchymal stem cells in cancer therapy
Cancer Lett. 2011 Jun 01;305(1):8-20, Long-Jun Dai, Mani R. Moniri, Zhi-Rong Zeng, Jeff X. Zhou, Jarrett Rayat, Garth L. Warnock
Abstract
Abstract
Mesenchymal stem cells (MSCs) are the first type of stem cells to be utilized in clinical regenerative medicine, mainly owing to their capacity for multipotent differentiation and the feasibility of autologous transplantation. More recently, the specific tumor-oriented migration and incorporation of MSCs have been demonstrated in various pre-clinical models, highlighting the potential for MSCs to be used as an ideal carrier for anticancer gene delivery. Engineered with specific anticancer genes,...
