Histologic Pitfalls in the Mohs Technique

Dermatol Clin. 2011 Apr;29(2):261-272, Navid Bouzari, Suzanne Olbricht

Abstract

Abstract

The success of the Mohs procedure depends on the reliability of each step in the technique. Pitfalls in histologic preparation of the tissue specimens may occur during debulking, excising, orienting, creating the map, sectioning, inking, tissue flattening and freezing, cutting, slide fixation, staining, and mapping the tumor. Challenges are also present in interpreting the slides. Diagnostic pitfalls include floaters, inflammatory conditions resembling tumor, and perineural invasion. The technique...

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