New Drugs in Melanoma: It's a Whole New World
New Drugs in Melanoma: It's a Whole New World
AMM Eggermont, C Robert
Yes
20110629
2011 Jul 29
Eur J Cancer
New Drugs in Melanoma: It's a Whole New World
Eur J Cancer. 2011 Jul 29;[Epub Ahead of Print], AMM Eggermont, C Robert
Abstract
Abstract
Current developments in systemic therapies for melanoma are spectacular. Over the last 40years no one drug or combination of drugs demonstrated any impact on survival in metastatic melanoma. In contrast, in 2011 a number of new drugs will be approved.In 2011 immunomodulation with ipilimumab, a monoclonal antibody targeting the ligand CTLA-4, has been approved for patients with advanced melanoma in first- and second-line treatment by the Food and Drug Administration (FDA) and in second-line treatment...