The Risk of Skin Rash and Stomatitis With the Mammalian Target of Rapamycin Inhibitor Temsirolimus: A Systematic Review of the Literature and Meta-Analysis
Risk of Skin Rash and Stomatitis With Temsirolimus
C Gomez-Fernandez, BC Garden, S Wu, DR Feldman, ME Lacouture
Yes
20111129
2011 Dec 29
Eur J Cancer
The Risk of Skin Rash and Stomatitis With the Mammalian Target of Rapamycin Inhibitor Temsirolimus: A Systematic Review of the Literature and Meta-Analysis
Eur J Cancer. 2011 Dec 29;[Epub Ahead of Print], C Gomez-Fernandez, BC Garden, S Wu, DR Feldman, ME Lacouture
Abstract
Abstract
Objective: We conducted a systematic review of the literature and performed a meta-analysis to determine the risk of developing skin rash and stomatitis among patients receiving temsirolimus.Methods: Databases from PubMed and Web of Science from January, 1998 until June, 2011 and abstracts presented at the American Society of Clinical Oncology annual meetings from 2004 through 2011 were searched to identify relevant studies. The incidence and relative risk (RR) of skin rash and stomatitis were calculated...
