Stage I Nonseminomatous Germ Cell Tumor of the Testis: More Questions than Answers?
What is Optimal Management for NSGCT?
T Powles
Yes
20110501
2011 Jun 1
Hematol Oncol Clin North Am
Yes
Stage I Nonseminomatous Germ Cell Tumor of the Testis: More Questions than Answers?
Hematol Oncol Clin North Am. 2011 Jun 1;25(3):517-527, T Powles
Abstract
Abstract
The outcome of patients with stage I nonseminomatous germ cell tumors (NSGCTs) is excellent, with 99% overall 5-year survival. If treated with orchiectomy alone, approximately 30% of patients relapse with metastatic disease. Therefore adjuvant therapy with either chemotherapy or retroperitoneal lymph node dissection (RPLND) is often recommended, despite impressive results with active surveillance alone. This article addresses the risks and benefits of each approach.
