Breast Cancer Occurred After Hodgkin's Disease: Clinico-Pathological Features, Treatments and Outcome: Analysis of 214 Cases

Crit Rev Oncol Hematol. 2012 Jan 1;81(1):29-37, B Cutuli, S Kanoun, C Tunon De Lara, M Velten

Abstract

Abstract

Background: Secondary tumours (ST) represent a major concern in survivors of Hodgkin's disease (HD). Breast cancer (BC) is the most frequent ST among young treated women.Material and Methods: One hundred and eighty-nine women treated for HD by radiotherapy (RT) and/or chemotherapy (CT) subsequently developed 214 BCs.Results: Median age at HD diagnosis was 25 years (34% were less than 20). Median interval between HD and BC was 18.6 years, with a 42-year median age at first BC. According to the TNM...

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