Treatment of Metastatic Breast Cancer: State-of-the-Art, Subtypes and Perspectives

Crit Rev Oncol Hematol. 2011 Dec 1;80(3):433-449, NS El Saghir, A Tfayli, HA Hatoum, Z Nachef, P Dinh, A Awada

Abstract

Abstract

Current treatment of metastatic breast cancer (MBC) aims at achieving meaningful clinical responses, improved quality of life, long-term remissions, prolonged survival, and dares to hope for a cure in a small percentage of cases. This article will discuss both consensus and controversies in the management of MBC in the context of the new evolving breast cancer molecular classification. Hormonal therapy remains the mainstay of management of MBC Luminal A and B. Data is emerging on management of ErbB2-positive...

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