Advances and Applications of Oral Cancer Basic Research

Oral Oncol. 2011 Sept 1;47(9):783-791, SD da Silva, A Ferlito, RP Takes, RH Brakenhoff, MVD Valentin, JA Woolgar, CR Bradford, JP Rodrigo, A Rinaldo, MP Hier, LP Kowalski

Abstract

Abstract

Cancer of the oral cavity accounts for almost 3% of cancer cases in the world. The incidence varies widely reflecting geographic differences in exposure to risk factors. The recent rise in younger age groups and females seen in many countries is of particular concern. Treatment and management of complications, locoregional recurrence and further primary tumors result in high morbidity and mortality especially when the disease is advanced stage at initial diagnosis. Progress in cancer research has...

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