The Role of Neck Dissection in the Setting of Chemoradiation Therapy for Head and Neck Squamous Cell Carcinoma With Advanced Neck Disease

Oral Oncol. 2011 Nov 20;[Epub Ahead of Print], M Hamoir, A Ferlito, S Schmitz, RP Takes, et al

Abstract

Abstract

Concurrent chemotherapy and radiotherapy (CRT) has become standard treatment for many patients with advanced head and neck squamous cell carcinoma (HNSCC). This has led to controversy concerning the role of neck dissection (ND) in this setting. The current debate is focused on N2–N3 disease and the ability of a clinical complete response to predict the absence of viable cells in the ND specimen. Proponents of a systematic planned ND argue that it improves regional control and possibly disease-specific...

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