VEGF and EMMPRIN expression correlates with survival of patients with osteosarcoma
Quan Zhou, Yong Zhu, Zhansheng Deng, Haitao Long, Shaoxian Zhang, Xingli Chen
20110201
2011 Mar 1
Surg Oncol
VEGF and EMMPRIN expression correlates with survival of patients with osteosarcoma
Surg Oncol. 2011 Mar;20(1):13-19, Quan Zhou, Yong Zhu, Zhansheng Deng, Haitao Long, Shaoxian Zhang, Xingli Chen
Abstract
Abstract
AimTo investigate the clinicopathologic characteristics of Vascular Endothelial Growth Factor (VEGF) and Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) expression in osteosarcoma, and to evaluate the clinical significance of these two markers in the survival of osteosarcoma.MethodsVEGF and EMMPRIN expression in paraffin-embedded specimens gathered from 65 patients with primary osteosarcoma were detected by the method of immunohistochemistry using antibodies against VEGF and EMMPRIN. The...
