Cardiac Toxicity in Breast Cancer Patients: From a Fractional Point of View to a Global Assessment

Cancer Treat Rev. 2011 Jun;37(4):321-330, C Chargari, KM Kirov, MA Bollet, N Magné, L Védrine, S Cremades, P Beuzeboc, A Fourquet, YM Kirova

Abstract

Abstract

When focusing on heart disease, most available studies split the two different parts of the adjuvant treatment, i.e., systemic therapies and radiation therapy, making it difficult to implement efficient strategies for preventing treatment-induced cardiac toxicity. This paper reviews the current understanding of treatments-induced cardiac toxicity in a global approach. Many factors should be considered when assessing the cardiac hazard. Treatment-related risk factors include heart dose exposure, chemotherapy,...

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