Use of molecular markers for predicting therapy response in cancer patients
Michael J. Duffy, Norma O’Donovan, John Crown
20110301
2011 Apr 1
Cancer Treat Rev
Use of molecular markers for predicting therapy response in cancer patients
Cancer Treat Rev. 2011 Apr;37(2):151-159, Michael J. Duffy, Norma O’Donovan, John Crown
Abstract
Abstract
Predictive markers are factors that are associated with upfront response or resistance to a particular therapy. Predictive markers are important in oncology as tumors of the same tissue of origin vary widely in their response to most available systemic therapies. Currently recommended oncological predictive markers include both estrogen and progesterone receptors for identifying patients with breast cancers likely to benefit from hormone therapy, HER-2 for the identification of breast cancer patients...
