Carboplatin Is as Effective as Radiation in Early-stage Testicular Cancer

Elsevier Global Medical News. 2008 Jun 19, P Wendling

CHICAGO (EGMN) – A single dose of carboplatin is less toxic and just as effective in preventing disease recurrence as adjuvant radiotherapy in men with stage I seminoma after orchiectomy, according to findings from the largest study ever in testicular cancer. In an intent-to-treat analysis, the relapse-free rates at 5 years were 94.7% for the carboplatin arm and 96% for the radiotherapy arm (hazard ratio, 1.25; P = .37), according to findings presented in a plenary session at the annual meeting of...

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