Gastric Cancer Subtype May Affect Bevacizumab Benefit

Elsevier Global Medical News. 2012 Jan 25, S London

SAN FRANCISCO (EGMN) - The benefit of bevacizumab in some patients with advanced gastric cancer appears to vary by disease subtype, based on an exploratory analysis of data from the phase III AVAGAST trial.The global trial randomized 774 patients to chemotherapy plus placebo or bevacizumab (Avastin), an antibody to vascular endothelial growth factor (VEGF). Results for the entire trial population, which were reported previously (J. Clin. Oncol. 2011;29:3968-76), showed no significant gain in overall...

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