Higher doses of opioids - the equivalent of 50 mg/dL or more of morphine - are more likely than are lower doses to lead to unintentional overdose, according to a report in the April 6 issue of JAMA. However, the practice of adding a prescription for as-needed opioids to an existing prescription for regularly scheduled opioids, which allows patients to deal with acute exacerbations of pain, does not raise the risk of unintentional overdose in most patients, as some experts have feared, said Amy S.B....