Ask the Expert: Applying BOLERO-2 to the “Hormone-Refractory” Patient
Applying BOLERO-2 to the “Hormone-Refractory” Patient
Clifford Hudis, MD
20120030
2012 Jan 30
Ask the Expert: Applying BOLERO-2 to the “Hormone-Refractory” Patient
2012 Jan 30, Clifford Hudis, MD
"Ask the Expert” features answers by our experts to your clinical questions. Question: How do we apply the data from the BOLERO-2 trial to practice? Can we “re-challenge” a patient with metastatic ER-positive breast cancer, who is hormone-refractory and has already progressed through a few lines of chemotherapy, with exemestane and everolimus?Answer: I would consider everolimus along with exemestane for patients who would have been eligible for BOLERO-2 as presented. This question asks, “Can we...
