Ask the Expert: What’s the Role for Post-Mastectomy Radiation and Chemotherapy in Node-Positive Breast Cancer?

2012 Jan 30, Clifford Hudis, MD

"Ask the Expert” features answers by our experts to your clinical questions. Question: Is it safe to avoid post-mastectomy irradiation in patients with 1-3 positive axillary lymph nodes?How would you determine the relative importance of age, lymphovascular invasion, differentiation, prognostic groups (luminal A, B, HER2, or TNC), and Ki67 status in deciding to administer adjuvant chemotherapy and/or radiation therapy?What is the role of genetic tests in this specific group of patients?Answer: The...

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